December 9, 2024
By Neurological Institute of Los Angeles (NILA)
Scientists have found a new way to treat chronic pain. They discovered a natural substance called hederagenin that blocks a part of the brain and spinal cord called the NPFFR1 receptor. This receptor plays a big role in how we feel pain.
This discovery could lead to new medicines that help people with long-term pain feel better.
What is NPFFR1?
It is a part of the brain and spinal cord that helps control pain. Scientists want to block it to stop pain signals.
What is Hederagenin?
It is a natural substance found in ivy plants. Scientists found it can block the NPFFR1 receptor and stop pain without harming other parts of the body.
How Did Scientists Find This?
They used advanced tests and computer models to see how hederagenin works. They also studied how it connects to the NPFFR1 receptor.
Millions of people live with chronic pain. Current treatments don’t always work well or can cause side effects. This discovery is a step toward making better and safer medicines for pain.
Researchers from different fields, like medicine and computer science, worked together to make this discovery. Professor Beck-Sickinger, one of the leaders of the project, said:
"This work shows how basic research can create new ways to help people."
Scientists will keep studying hederagenin to turn this discovery into real medicines. This gives hope to many people who live with pain every day.
At NILA, we bring the latest science to help our patients. If you or someone you know struggles with chronic pain, contact us to learn about the treatments we offer.
Tags: Chronic Pain, Neuroscience, Pain Relief, NPFFR1, Hederagenin, Neurology
